Red Sox vs. Astros: Pitching Matchup, Injury Report & Game Preview

Red Sox vs. Astros: A Wednesday Afternoon Battle in Houston

The Boston Red Sox (1-4) head to Houston to face the Astros (4-2) this Wednesday, with first pitch scheduled for 2:10 p.m. EDT. Both teams are looking to build momentum early in the season, and this interleague matchup promises an exciting contest. Let’s dive into the pitching matchup, injury reports, and team stats to preview this game.

Pitching Probables

Red Sox: Garrett Crochet (1-0, 0.00 ERA, 0.83 WHIP, 8 strikeouts) takes the mound for Boston. Crochet has started the season strong, showcasing impressive control and strikeout ability. He’ll be a key factor in keeping the Astros’ potent offense at bay.

Astros: Mike Burrows (0-1, 7.94 ERA, 1.94 WHIP, 6 strikeouts) is slated to pitch for Houston. Burrows will be looking to bounce back from a rough start and find his rhythm against a Red Sox lineup that has shown flashes of power.

Team Stats & Performance

The Houston Astros finished the 2025 season with an 87-75 record, boasting a strong 46-35 record at home. They averaged 8.5 hits per game, with 2.7 extra-base hits, demonstrating their ability to manufacture runs. The Astros’ offense is a significant threat, and the Red Sox pitching staff will need to be sharp.

The Boston Red Sox also had a successful 2025 campaign, posting an 89-73 record overall. However, their road record was a more modest 41-40. Boston’s pitching staff maintained a collective 3.71 ERA last season, averaging 8.5 strikeouts and 3.3 walks per nine innings. Controlling the strike zone will be crucial against the Astros.

Injury Report: Key Players Sidelined

Both teams are dealing with a significant number of injuries, which could impact the outcome of this game.

Astros Injuries

Hayden Wesneski: 60-Day IL (elbow)
Brandon Walter: 60-Day IL (elbow)
Nate Pearson: 15-Day IL (elbow)
Zach Dezenzo: 10-Day IL (elbow)
Ronel Blanco: 15-Day IL (elbow)
Bennett Sousa: 15-Day IL (oblique)
Enyel De Los Santos: 15-Day IL (knee)
Josh Hader: 15-Day IL (biceps)

Red Sox Injuries

Patrick Sandoval: 15-Day IL (elbow)
Kutter Crawford: 15-Day IL (wrist)
Anthony Seigler: 10-Day IL (knee)
Triston Casas: 10-Day IL (knee)
Romy Gonzalez: 60-Day IL (shoulder)
Tanner Houck: 60-Day IL (elbow)

These injuries will force both managers to rely on depth and potentially give opportunities to younger players. Keep an eye on how these absences affect team performance.

Looking Ahead

This Wednesday afternoon matchup between the Red Sox and Astros is shaping up to be a compelling contest. With a strong pitching duel expected and key players sidelined due to injury, every play will matter. Stay tuned for updates and analysis as the game unfolds!

This story was created using technology provided by Data Skrive and data from Sportradar, and was originally published by The Associated Press.