Eric Dane Dies at 53 After ALS Diagnosis

Los Angeles mourns the loss of Eric Dane, the charismatic actor best known for his portrayal of Dr. Mark Sloan on the hit series Grey’s Anatomy. Dane passed away on Thursday afternoon at the age of 53, following a valiant battle with Amyotrophic Lateral Sclerosis (ALS), according to a statement released by his family. The news has sent shockwaves through the entertainment industry and deeply saddened fans worldwide.

A Public Battle with ALS

Dane publicly revealed his ALS diagnosis just ten months prior to his passing, bravely sharing his journey with the world. ALS, a progressive neurodegenerative disease, affects nerve cells in the brain and spinal cord, leading to muscle weakness, difficulty speaking, and eventually, loss of mobility. The National Institute of Neurological Disorders and Stroke explains that the average life expectancy after diagnosis is typically three to five years, though some individuals may live longer.

Career and Recent Projects

Fans first grew concerned when Dane was unable to attend the Emmy Awards in September 2025, where he was scheduled to present an award. A subsequent announcement revealed he was receiving treatment for a fall. Despite his declining health, Dane remained committed to his craft. He continued to work, taking on a role in the series Brilliant Minds in the fall of 2025. His portrayal of a firefighter battling ALS resonated deeply with audiences, raising awareness about the devastating disease.

Advocacy and Family

Dane became a vocal advocate for ALS awareness and research shortly after his diagnosis. He tirelessly fundraised for research initiatives and openly discussed the challenges of living with the disease. In a poignant interview with Diane Sawyer, he spoke candidly about the rapid progression of his condition, stating, “I will never forget these three letters. ALS. It hits me the moment I wake up. It’s not a dream.” He expressed concern about the impact his illness would have on his daughters, Billie and Georgia, whom he shared with his wife, Rebecca Gayheart. The couple, who had previously considered divorce, decided to remain together to support each other and their children during this difficult time.

A Lasting Legacy

Eric Dane’s passing is a profound loss. He will be remembered not only for his talent and captivating performances but also for his courage, vulnerability, and dedication to raising awareness about ALS. His work will continue to inspire and his memory will live on in the hearts of his fans. He was a true advocate, and his story serves as a powerful reminder of the importance of continued research and support for those affected by this devastating disease. You can learn more about ALS and how to support research efforts at the ALS Association.